1. *Turku Centre for Biotechnology, University of Turku, Åbo Akademi University, 20520 Turku, Finland;
2. Departments of †Biochemistry and Pharmacy and
3. Biology, Åbo Akademi University, 20520 Turku, Finland; and
4. Institut National de la Santé et de la Recherche Médicale, U823, Institut Albert Bonniot; Université Joseph Fourier, Institut Albert Bonniot, Grenoble 38700, France