Meiosis II spindle disassembly requires two distinct pathways

Abstract

AMA1 and SPS1 control distinct aspects of meiosis II spindle disassembly, with AMA1 affecting the loss of Ase1 and Cin8 during meiosis II spindle disassembly, while SPS1 affects Bim1. The Anaphase Promoting Complex and meiotic/mitotic exit pathways seem to regulate similar targets in meiosis as mitosis, despite utilizing meiosis-specific regulators in those pathways.