Affiliation:
1. Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520
Abstract
The trans-Golgi network coordinates sorting and secretion of proteins and lipids to cellular organelles and the plasma membrane. It is revealed that Sdc1, a heparin sulfated proteoglycan present on basolateral membranes of polarized epithelia, requires the golgin GOPC for basolateral targeting, in contrast to its sorting requirements in nonpolarized cells.
Publisher
American Society for Cell Biology (ASCB)
Subject
Cell Biology,Molecular Biology
Cited by
1 articles.
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