Lgd regulates ESCRT-III complex accumulation at multivesicular endosomes to control intralumenal vesicle formation-Reference-Cited by-同舟云学术

Lgd regulates ESCRT-III complex accumulation at multivesicular endosomes to control intralumenal vesicle formation

Published:2022-12-01 Issue:14 Volume:33 Page:
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Clarke Aryel L.¹,Lettman Molly M.¹,Audhya Anjon¹

Affiliation:

1. Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705

Abstract

Lgd is targeted to multivesicular endosomes in a manner dependent on components of the ESCRT machinery and the presence of acidic phospholipids. There, it functions to promote stable ESCRT-III complex assembly to facilitate the formation of intralumenal vesicles within endosomes.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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