Mammalian Septins Nomenclature-Reference-Cited by-同舟云学术

Mammalian Septins Nomenclature

Published:2002-12 Issue:12 Volume:13 Page:4111-4113
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Macara Ian G.¹,Baldarelli Richard²,Field Christine M.³,Glotzer Michael⁴,Hayashi Yasuhide⁵,Hsu Shu-Chan⁶,Kennedy Mary B.⁷,Kinoshita Makoto³,Longtine Mark⁸,Low Claudia⁹,Maltais Lois J.²,McKenzie Louise²,Mitchison Timothy J.³,Nishikawa Toru¹⁰,Noda Makoto¹¹,Petty Elizabeth M.¹²,Peifer Mark¹³,Pringle John R.¹³,Robinson Phillip J.¹⁴,Roth Dagmar¹⁵,Russell S.E. Hilary¹⁶,Stuhlmann Heidi¹⁷,Tanaka Manami¹⁸,Tanaka Tomoo¹⁹,Trimble William S.²⁰,Ware Jerry²¹,Zeleznik-Le Nancy J.²²,Zieger Barbara²³

Affiliation:

1. Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908;

2. Mouse Genome Informatics, Jackson Laboratories, Bar Harbor, Maine 04609;

3. Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115;

4. Research Institute of Molecular Pathology, A-1030 Vienna, Austria;

5. Department of Pediatrics, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655, Japan;

6. Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854;

7. Division of Biology, California Institute of Technology, Pasadena, California 91125;

8. Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078;

9. Department of Biochemistry, University of Virginia School of Medicine, Charlottesville, Virginia 22908;

10. Section of Psychiatry and Behavioral Sciences, Tokyo Medical and Dental University Graduate School, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8519, Japan;

11. Department of Molecular Oncology, Kyoto University Graduate School of Medicine, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan;

12. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109;

13. Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599;

14. Cell Signaling Unit, Children's Medical Research Institute, Wentworthville 2145, New South Wales, Australia;

15. Max-Planck-Institute for Brain Research, Department of Neurochemistry, Frankfurt, and Covidence GmbH, Philipp-Helfmann-Strasse 18, D-65760 Eschborn, Germany;

16. Department of Oncology, Queen's University of Belfast, Belfast BT9 7AB, United Kingdom;

17. Department of Biochemistry and Molecular Biology, Mount Sinai School of Medicine, New York, New York 10029;

18. National Institute of Advanced Industrial Science and Technology, Bldg. Tsukuba Central 6, Higashi, Tsukuba Science City, Ibaraki 305-8566, Japan;

19. Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan;

20. Program in Cell Biology, Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada;

21. The Scripps Research Institute, La Jolla, California 92037;

22. Cardinal Bernardin Cancer Center and Department of Medicine, Loyola University Medical, Center, Maywood, Illinois 60153; and

23. Department of Pediatrics and Adolescent Medicine, Children's Hospital, University of Freiburg, D-79106 Freiburg, Germany

Abstract

There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophilaseptins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be namedSEPT1–SEPT10 and Sept1–Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase “v” and a number, e.g., SEPT4_v1.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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