Forty-five years of cell-cycle genetics-Reference-Cited by-同舟云学术

Forty-five years of cell-cycle genetics

Published:2015-12 Issue:24 Volume:26 Page:4307-4312
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Reid Brian J.¹²,Culotti Joseph G.³⁴,Nash Robert S.⁵⁶,Pringle John R.⁶

Affiliation:

1. Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA 98109

2. Departments of Genome Sciences and Medicine, University of Washington, Seattle, WA 98195

3. Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada

4. Department of Molecular Genetics, University of Toronto, Toronto, ON M5G 1X5, Canada

5. Saccharomyces Genome Database, Stanford University School of Medicine, Stanford, CA 94305

6. Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305

Abstract

In the early 1970s, studies in Leland Hartwell’s laboratory at the University of Washington launched the genetic analysis of the eukaryotic cell cycle and set the path that has led to our modern understanding of this centrally important process. This 45th-anniversary Retrospective reviews the steps by which the project took shape, the atmosphere in which this happened, and the possible morals for modern times. It also provides an up-to-date look at the 35 original CDC genes and their human homologues.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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