Receptor-type protein tyrosine phosphatase alpha (PTPα) mediates MMP14 localization and facilitates triple-negative breast cancer cell invasion-Reference-Cited by-同舟云学术

Receptor-type protein tyrosine phosphatase alpha (PTPα) mediates MMP14 localization and facilitates triple-negative breast cancer cell invasion

Published:2021-04-01 Issue:7 Volume:32 Page:567-578
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Decotret Lisa R.¹²³,Wadsworth Brennan J.¹³,Li Ling Vicky²³,Lim Chinten J.²³⁴,Bennewith Kevin L.¹³,Pallen Catherine J.²³⁴

Affiliation:

1. Integrative Oncology, BC Cancer, Vancouver, British Columbia, BC V5Z 4E6, Canada

2. Michael Cuccione Childhood Cancer Research Program, BC Children’s Hospital Research Institute, Vancouver, British Columbia, BC V5Z 4H4, Canada

3. Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, BC V6H 3V4, Canada

4. Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, BC V6H 3V4, Canada

Abstract

Protein tyrosine phosphatase alpha (PTPα) regulates breast tumor cell invasion in vitro and in vivo, implicating PTPα as a potential therapeutic target for limiting the spread of triple-negative breast cancer.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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