F–actin-bundling sites are conserved in proteins with villin-type headpiece domains-Reference-Cited by-同舟云学术

F–actin-bundling sites are conserved in proteins with villin-type headpiece domains

Published:2020-08-01 Issue:17 Volume:31 Page:1857-1866
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

George Sudeep P.¹,Esmaeilniakooshkghazi Amin¹,Roy Swati¹,Khurana Seema¹²

Affiliation:

1. Department of Biology and Biochemistry, University of Houston, Houston, TX 77044

2. Department of Allied Health, Baylor College of Medicine, Houston, TX 77030

Abstract

Villin is a major actin-bundling protein that assembles the microvilli of intestinal and renal epithelial cells. Using the nuclear magnetic resonance structure of the isolated villin and advillin headpiece proteins and mutational analysis in full-length proteins, we identify the actin-bundling site in human villin and proteins with villin-type headpiece domain.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference40 articles.

1. Villin: The major microfilament-associated protein of the intestinal microvillus

2. Involvement of advillin in somatosensory neuron subtype-specific axon regeneration and neuropathic pain

3. Cysteine Scanning Mutagenesis at 40 of 76 Positions in Villin Headpiece Maps the F-Actin Binding Site and Structural Features of the Domain

4. Microinjection of villin into cultured cells induces rapid and long-lasting changes in cell morphology but does not inhibit cytokinesis, cell motility, or membrane ruffling.

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bsp1, a fungal CPI motif protein, regulates actin filament capping in endocytosis and cytokinesis;Molecular Biology of the Cell;2024-02-01

2. Bsp1, a fungal CPI motif protein, regulates actin filament capping in endocytosis and cytokinesis;2023-10-10

3. The Potential for Targeting AVIL and Other Actin-Binding Proteins in Rhabdomyosarcoma;International Journal of Molecular Sciences;2023-09-17

4. Targeting AVIL, a New Cytoskeleton Regulator in Glioblastoma;International Journal of Molecular Sciences;2021-12-20

5. Mechanical Behavior of Axonal Actin, Spectrin, and Their Periodic Structure: A Brief Review;Multiscale Science and Engineering;2021-08-04