Mechanistic insights into actin-driven polarity site movement in yeast-Reference-Cited by-同舟云学术

Mechanistic insights into actin-driven polarity site movement in yeast

Published:2020-05-01 Issue:10 Volume:31 Page:1085-1102
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Ghose Debraj¹²,Lew Daniel²

Affiliation:

1. Computational Biology and Bioinformatics, Duke University Medical Center, Durham, NC 27710

2. Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710

Abstract

Cells dynamically orient their direction of growth or movement by moving a polarity site that defines the front. A bottom-up computational model is used to explore the mechanism of movement. Assumptions inspired by findings in the yeast system show that vesicle traffic directed to the polarity site would suffice to produce realistic movement.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference82 articles.

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3. Activator–inhibitor coupling between Rho signalling and actin assembly makes the cell cortex an excitable medium

4. Cdc42 Explores the Cell Periphery for Mate Selection in Fission Yeast

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