XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions-Reference-Cited by-同舟云学术

XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions

Published:2020-09-15 Issue:20 Volume:31 Page:2187-2194
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

King Brianna R.¹,Moritz Michelle²,Kim Haein³,Agard David A.²,Asbury Charles L.³,Davis Trisha N.¹

Affiliation:

1. Department of Biochemistry, University of Washington, Seattle, WA 98195

2. Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158

3. Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195

Abstract

XMAP215 promotes microtubule nucleation independently as a polymerase of nucleation intermediates. Across a range of polymerase activities, XMAP215 and γ-tubulin function additively, indicating independent modes of action. Any synergistic behavior must arise from unique interactions made in the context of the γ-TuRC.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference51 articles.

1. Tension directly stabilizes reconstituted kinetochore-microtubule attachments

2. Insights into microtubule nucleation from the crystal structure of human γ-tubulin

3. A tethered delivery mechanism explains the catalytic action of a microtubule polymerase

4. XMAP215 Is a Processive Microtubule Polymerase

5. Regulation of the microtubule nucleating activity of centrosomes in Xenopus egg extracts: role of cyclin A-associated protein kinase.

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mechanism of how the universal module XMAP215 γ-TuRC nucleates microtubules;2024-06-03

2. CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC;Nature Cell Biology;2024-02-29

3. Advancements in the study of synaptic plasticity and mitochondrial autophagy relationship;Journal of Neuroscience Research;2024-02

4. Conformational states of the microtubule nucleator, the γ-tubulin ring complex;2023-12-20

5. Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes;Journal of Cell Biology;2023-09-12