Centrosomes are required for proper β-catenin processing and Wnt response-Reference-Cited by-同舟云学术

Centrosomes are required for proper β-catenin processing and Wnt response

Published:2020-08-01 Issue:17 Volume:31 Page:1951-1961
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Vora Setu M.¹,Fassler Jan S.¹,Phillips Bryan T.¹

Affiliation:

1. Department of Biology, University of Iowa, Iowa City, IA 52242-1324

Abstract

The Wnt/β-catenin pathway is a key cell signaling module utilized in cell fate specification. Recent studies suggest an interplay between Wnt/β-catenin signaling components and centrosome function. This study explores the net effects of centrosome loss on Wnt signaling and posttranslational β-catenin regulation.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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