Genetic suppression of defective profilin by attenuated Myosin II reveals a potential role for Myosin II in actin dynamics in vivo in fission yeast-Reference-Cited by-同舟云学术

Genetic suppression of defective profilin by attenuated Myosin II reveals a potential role for Myosin II in actin dynamics in vivo in fission yeast

Published:2020-09-01 Issue:19 Volume:31 Page:2107-2114
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Zambon Paola¹,Palani Saravanan¹,Jadhav Shekhar Sanjay²,Gayathri Pananghat²,Balasubramanian Mohan K.¹

Affiliation:

1. Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom

2. Biology Division, Indian Institute of Science Education and Research, Pune, Maharashtra 411008, India

Abstract

This work reveals an in vivo role for Myosin II in actin dynamics, potentially in its disassembly and turnover. The work uses double mutant analysis to arrive at this conclusion using the fission yeast as a model organism.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference54 articles.

1. High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A

2. Fission yeast Sop2p: a novel and evolutionarily conserved protein that interacts with Arp3p and modulates profilin function.

3. A new tropomyosin essential for cytokinesis in the fission yeast S. pombe

4. The Schizosaccharomyces pombe cdc3+ gene encodes a profilin essential for cytokinesis.

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