Ersonified diagnostic and correction dyslipidemia approach by profiling of apolipoproteins-Reference-Cited by-同舟云学术

Ersonified diagnostic and correction dyslipidemia approach by profiling of apolipoproteins

Published:2020-12-31 Issue:4 Volume: Page:88-104
ISSN:2226-762X
Container-title:Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)
language:
Short-container-title:jour

Author:

Kachkovsky M. A.¹,Vvedenskaya I. P.²,Vvedensky V. Yu.³,Supilnikov A. A.¹,Ponomareva J. V.⁴,Milyakova M. N.¹

Affiliation:

1. Private institution educational organization of higher education "Medical University Reavies

2. Federal State Budgetary Institution of Higher Education «Samara State Medical University» Ministry of Health of the Russian Federation

3. State Budgetary Institution of Samara Region Otradnenskaya Municipal Hospital

4. ARTBIO LLC

Abstract

Many questions remain in the diagnosis, treatment, and prevention of dyslipidemia, despite the available clinical recommendations. Among these issues is the cause of cardiovascular diseases, when achieving and maintaining the target values of lipid metabolism. We need to change the existing paradigm. Apolipoproteins as protein components of lipoproteins can significantly more accurately characterize the dyslipidemic status of a patient, since their structure and composition are unique. A personalized strategy for the prevention and treatment of dyslipidemia is possible based on the apolipoprotein profile. At present, new data on the functions of apolipoproteins, their genetic polymorphisms, and molecular preparations for correcting their content and lipid metabolism have been proposed.

Publisher

Reaviz Medical University

Subject

General Medicine

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