Affiliation:
1. Samara State Medical University
2. Medical University "Reaviz"
3. Saratov State Medical University named after V.l. Razumovsky
Abstract
Anxiety is a natural survival mechanism that helps to cope with potentially dangerous situations. It is accompanied by changes in the functioning of the nervous and endocrine systems, which affect the behavior of living beings. It is possible to establish the level of anxiety and the severity of depression thanks to various behavioral methods, with the help of which it is possible to fix indicators, establish their duration, and then compare data on the emotional state of animals from the control and experimental groups. The purpose of the study: to identify the features of the emotional state of the offspring of rats that received an aqueous plant extract of reddish hellebore. Conclusions: aquatic plant extract of reddish hellebore has a modeling effect that reduces the level of anxiety and depression.
Publisher
Reaviz Medical University
Reference8 articles.
1. 1 Mamylina N.V., Pavlova V.I. Physiological aspects of behavioral activity of animals under emotional stress: monograph. Chelyabinsk. 2013:298. (In Russ).
2. 2 Pavlova O.N., Gulenko O.N., Temkin M.L., Zhelonkin N.N., Devyatkin A.A., Kanaeva E.S., Khabibullina T.V. Study of the emotional state of the offspring of rats treated with aqueous plant extracts. International Scientific Research Journal. 2022;11. (In Russ).
3. 3 Kaluev A.V. Studying anxiety in animals – yesterday, today, tomorrow. Stress and behavior: Materials of the 7th Interdisciplinary Conference on Biological Psychiatry. M. 2003;145–148. (In Russ).
4. 4 Kade A.H., Kravchenko S.V., Trofimenko A.I., Polyakov P.P., Lipatova A.S., Ananyeva E.I., etc. Modern methods of assessing the level of anxiety of rodents in behavioral tests based on models without prior conditioning. Kuban Scientific Medical Bulletin. 2018;25(6):171—176. (In Russ).
5. Lyubimov В.I. et al. Methodological recommendations for the preclinical study of the reproductive toxicity of pharmacological agents. Biomedical Journal Medline. ru. 2006. 26 Nov. URL: http://www.medline.rU/public/fund/pharmcom/4.phtmlom/4.phtml (In Russ)].