Dimeglumin chlorin E6 as a photo-sensitizer in photodynamic therapy in non-oncological diseases-Reference-Cited by-同舟云学术

Dimeglumin chlorin E6 as a photo-sensitizer in photodynamic therapy in non-oncological diseases

Published:2023-09-11 Issue:4 Volume:13 Page:57-62
ISSN:2782-1579
Container-title:Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH)
language:
Short-container-title:vmirvz

Author:

Semenov D. Yu.¹^ORCID,Shubin V. K.¹^ORCID,Stranadko E. F.²^ORCID,Komarov R. N.³^ORCID,Ryabov M. V.²^ORCID,Bogomazov Yu. K.¹^ORCID,Morokhotov V. A.¹,Shcherbyuk A. N.¹^ORCID,Morozov S. V.¹,Zakharov Yu. I.¹^ORCID,Bondarenko E. V.¹^ORCID,Karpov N. V.¹^ORCID,Flegontov P. B.¹^ORCID

Affiliation:

1. Moscow Regional Research Clinical Institute named after M.F. Vladimirsky

2. Scientific and Practical Center of Laser Medicine named after O.K. Skobelkin

3. First Sechenov Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)

Abstract

This review demonstrates the possibilities of photodynamic therapy in treatment of non-tumor pathologies using dimeglumine chlorin E6 as a photosensitizer. Initially, the method was invented for the treatment of cancer and demonstrated its effectiveness and safety. In present photodynamic therapy successfully used in the treatment of the bronchus, skin, stomach, cervix, larynx cancer. In addition to the treatment of different localization tumors, various studies demonstrated other positive effects of photodynamic therapy: antimicrobial, antimycotic, autoimmune, reparative. In the presented review, dimeglumine chlorin E6, which is a derivative of chlorin e6, acts as a photosensitizer. It demonstrates safety, high selectivity of accumulation in tissues, and is characterized by a short period of excretion from the body. Using of dimeglumine chlorin E6 cans significantly reduce the number of side effects associated with long-term skin phototoxicity.

Publisher

Reaviz Medical University

Subject

General Medicine

Reference29 articles.

1. 1 Stranadko E.F., Kuleshov I.Yu., Karakhanov G.Ya. Photodynamic effects on pathogenic microorganisms (current state of the problem of antimicrobial photodynamic therapy). Laser medicine. 2010;14(2):52-56. (In Russ).

2. 2 Yang Y., Hu Y., Wang H. Targeting antitumor immune response for enhancing the efficacy of photodynamic therapy of Cancer: recent advances and future perspectives. Oxidative Med. Cell. Longev. 2016.

3. 3 Yano T., Wang K.K. Photodynamic therapy for gastrointestinal cancer. Photochem Photobiol. 2019.

4. 4 Civantos F.J., Karakullukcu B., Biel M. et al. A Review of Photodynamic Therapy for Neoplasms of the Head and Neck. Advances in Therapy. 2018;35:324-340.

5. 5 Kwiatkowski S., Knap B., Przystupski D. et al. Photodynamic therapy - mechanisms, photosensitizers and combinations. Biomed Pharma-cother. 2018;106:1098-1107.

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. PREPARATION AND STANDARDIZATION OF EXPERIMENTAL BATCHES OF "PHOTORAN E6, LYOPHILIZATE FOR THE PREPARATION OF SOLUTION FOR INFUSIONS", A DRUG FOR PHOTODYNAMIC THERAPY USING HOGWEED LEAVES AS RAW MATERIALS;Problems of Biological, Medical and Pharmaceutical Chemistry;2024-09-01