Surgical treatment of patients with mechanical jaundice syndrome caused by choledocholithiasis

Author:

Koryttsev V. K.1ORCID,Krasnoslobodtsev A. M.2ORCID,Frolova E. V.1ORCID,Dergal S. V.3ORCID

Affiliation:

1. Samara State Medical University

2. Samara State Medical University; N.I. Pirogov City Clinical Hospital No. 1

3. Samara State Medical University; Samara City Clinical Hospital No. 8

Abstract

Treatment of patients with mechanical jaundice remains an urgent problem of modern surgery. Approximately in a half of patients the cause of this syndrome is the presence of concrements in the common bile duct. Nowadays there are various variants of choledocholithiasis surgical treatment – open surgery on bile ducts and various variants of endoscopic interventions.Objective: to determine indications for open variants of surgical treatment of the syndrome of mechanical jaundice caused by choledocholithiasis.Material and methods. The work is based on the retrospective analysis of the treatment results of 78 patients with the syndrome of the mechanical jaundice caused by choledocholithiasis. Patients were divided into two groups depending on the way of the mechanical jaundice elimination. The first group included 20 patients who underwent open surgery, and the second group consisted of 58 patients after endoscopic interventions.Results. In the 1st group 4 patients died out of 20 patients, the lethality rate was 20%. In Group II 2 of 58 patients died, the lethality was 3%. The difference in the lethality indexes between the groups turned out to be statistically significant (p = 0,028).Conclusion. Open surgery is indicated in patients with contraindications to pneumoperitoneum application due to the second half of pregnancy or concomitant pathology of the cardiovascular and/or respiratory systems, in unsuccessful attempts to perform endoscopic intervention, and also in concomitant pancreatitis.

Publisher

Reaviz Medical University

Subject

General Medicine

Reference9 articles.

1. Gabriel S.A., Dynko V.Yu., Durleshter V.M. et al. Retrograde endoscopic interventions for mechanical jaundice. Bulletin of Surgical Gastroenterology. 2016;3:52. (In Russ).

2. Bekheit M., Smith R., Ramsay G. et al. Meta-analysis of laparoscopic transcystic versus transcholedochal common bile duct exploration for choledocholithiasis. BJS Open. 2019;3:249.

3. Navaratne Lalin, Martinez Isla Alberto Transductal versus transcystic laparoscopic common bile duct exploration: an institutional review of over four hundred cases. Surgical Endoscopy. 2021;35:437–438.

4. Khadjibaev F.A., Tilemisov S.O., Hashimov M.A. and others. Antegrade and retrograde cholangiography in the diagnosis of mechanical jaundice. Bulletin of Surgical Gastroenterology. 2016;3:76–76. (In Russ).

5. Syrén Е., Eriksson S., Enochsson L. et al. Risk factors for pancreatitis following endoscopic retrograde cholangiopancreatography. BJS Open. 2019;3:488–489.

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