The correlations of morphometric parameters of structures of the aortic root having practical significance in the surgical correction of the aortic valve

Author:

Odinokova S. N.1ORCID,Nikolenko V. N.2,Komarov R. N.1,Vinokurov I. A.1,Mnatsakanyan G. V.1,Belkharoeva R. Kh.1

Affiliation:

1. Sechenov First Moscow State Medical University

2. Sechenov First Moscow State Medical University; Lomonosov Moscow State University

Abstract

Successful reconstruction of the aortic valve requires the preliminary creation of the anatomical design of its image, which includes a set of parameters of the valves of a particular valve. Errors in operation at the stage of design of valve components are fraught with subsequent dysfunction. In the present, the optimal sizes of the aortic root and the valves of the aortic valve were evaluated and the presence and values of correlations between them were determined. Statistically significant anatomical and functional correlations of morphometric characteristics of aortic root structures were revealed to achieve the optimal level of their correspondence in autologous grafts during surgical correction of the aortic valve. The main morphometric parameters of the aortic root were analyzed on the example of 54 samples obtained post mortem from patients whose death occurred from causes not associated with heart disease. The cases with aortic valve disease were excluded from the study. The following parameters were evaluated: circumference of the ventriculo-arterial junction; circumference of the sinuses of Valsalva; circumference of the sinutubular junction. Separately, for each of the three cusps of the native aortic valve, were evaluated: the length of the free edge of the cusp (L1); the length of the junction of the leaflet and the fibrous ring of the aortic valve (L2); leaflet height (A); intercommissural distance (IC). A search was made for the correlation between the size of the valves and the parameters of the circumference of the aortic root at the level of the ventriculo-arterial junction, of the sinuses of Valsalva and of sinutubular junction. A significant presence of a correlations was found between all parameters of the aortic valve cusps and the length of the aortic circumference at the level of the ventriculo-arterial junction, of the sinuses of Valsalva and sinutubular junction (r>0.6 for IC, L1, L2 and r>0.5 for A at p<0,01). The data obtained by correlation analysis make it possible to standardize the design of the autograft of the aortic valve, thereby ensuring the best coaptation of the valves and, as a result, the function of the aortic valve.

Publisher

Reaviz Medical University

Subject

Energy Engineering and Power Technology,Fuel Technology

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