Non-Necrotizing Granulomas in Bone Marrow Biopsy of a Patient with Bicytopenia: Brucellosis Case

Abstract

Objective: Brucellosis has the ability to mimic a variety of multisystem illnesses, exhibiting a wide range of clinical polymorphism that frequently leads to misdiagnosis and treatment delays, thus raising the risk of complications. In cases of brucellosis, hematologic abnormalities might manifest as anemia, leukopenia, thrombocytopenia, lymphomonocytosis, hemolytic anemia, disseminated intravascular coagulation, and pancytopenia. Material and Methods: In this study, we presented the bone marrow biopsy findings of a brucellosis case. Case: For ten days, a 19-year-old male patient with fever, exhaustion, weight loss, loss of appetite, and stomach pain was taken to the emergency room. A bone marrow aspiration and biopsy were conducted because of the patient's indications and symptoms. Brucella melitensis was isolated in the blood and bone marrow cultures on the 7th day. Conclusion: Brucellosis, one of the most common zoonoses in the world and our country, can occur with a wide variety of complications.