Author:
Jadhav Praveen, ,Kulkarni Teja,Jadhav Janhavee,Desai Saourabh,Baviskar Rahul
Abstract
Systemic lupus erythematosus (SLE) is a rare autoimmune disorder in a physician’s practice, commonly presenting in young females. It is rare for SLE to present at a late age. Though SLE is idiopathic, sometimes it can present as an adverse reaction to drugs. Quite a few drugs are implicated in this process. However, there are no reports of levetiracetam causing SLE. Here, we present a case of 62-year-old female presenting with SLE after consumption of levetiracetam for 1 year for her epilepsy. Erythematosus rash was her main symptom. This was associated with a strong positivity of antinuclear antibody. The symptoms remitted completely after the discontinuation of levetiracetam, suggesting them to be because of drug-induced lupus (DIL). DIL differs from SLE in being mild, affecting atypical age groups and resolving completely on withdrawal of the drug.
Publisher
Royal College of Physicians of Edinburgh
Subject
Education,General Medicine
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Thrombosis and Anticoagulation Therapy in Systemic Lupus Erythematosus;Autoimmune Diseases;2022-06-27
2. Anti-epileptic medications;Side Effects of Drugs Annual;2022
3. Authors’ reply;Journal of the Royal College of Physicians of Edinburgh;2021-09
4. Levetiracetam-induced systemic lupus erythematosus or simply a drug-induced rash?;Journal of the Royal College of Physicians of Edinburgh;2021-09
5. Levetiracetam;Reactions Weekly;2021-05