Application of extracorporeal membrane oxygenation in newborns with refractory hypoxemia during medical evacuation

Author:

Yakovlev A. V.1ORCID,Trizna E. V.1ORCID,Nokhrin A. V.1ORCID,Suvorov V. V.1ORCID,Khatagova R. B.1ORCID,Kiriakov K. S.1ORCID,Solovieva E. A.1ORCID,Pshenisnov K. V.1ORCID

Affiliation:

1. St. Petersburg State Pediatric Medical University

Abstract

Extracorporeal membrane oxygenation is a modern therapeutic strategy aimed to stabilize vital function in a patient suffering from severe circulatory failure and refractory hypoxia.Purpose. To describe two clinical cases of venoarterial extracorporeal membrane oxygenation in neonates with mеconium aspiration syndrome, complicated by persistent pulmonary hypertension and refractory hypoxia during medical evacuation.Material and methods. The authors performed a comprehensive analysis of the condition specifics based on clinical and instrumental work up.Results. We demonstrated that early application of venoarterial extracorporeal membrane oxygenation in neonates with meconium aspiration syndrome promotes the quickest possible stabilization and reverse of hypoxia and low cardiac output.Conclusion. Venoarterial extracorporeal membrane oxygenation in neonates with meconium aspiration syndrome and refractory hypoxemia is a life-saving procedure, that can be applied during medical evacuation by qualified medical staff.

Publisher

The National Academy of Pediatric Science and Innovation

Subject

Pediatrics, Perinatology and Child Health

Reference14 articles.

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3. Khubulava G.G., Naumov A.B., Marchenko S.P., Suvorov V.V., Averkin I.I., Nevmerzhitskaya O.V. et al. Evaluating the effectiveness of resuscitation with extracorporeal membrane oxygenation in a model of acute hypoxic cardiac arrest in pigs (experimental study). Pediatr 2014; 4: 20–26. (in Russ.)

4. Maltseva O.S., Pshenisnov K.V., Shelukhin D.A. Naumov A.B., Marchenko S.P., Yakovlev A.V. et al. Extracorporal membrane oxygenation in pediatrics and the neonatology. Meditsina: teoriya i praktika 2018; 3(4): 108–114. (in Russ.)

5. Bokeriya L.A., Shatalov K.V., Lobacheva G.V., Har’kin A.V., Mahalin M.V., Brodskij A.G. et al. Method of extracorporeal membrane oxygenation in the treatment of heart failure in early age children in cardiac clinic. Detskiye bolezni serdtsa i sosudov 2012; 1: 19–25. (in Russ.)

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