Comparative analysis of the effectiveness of local therapy of chronic tonsillitis in children-Reference-Cited by-同舟云学术

Comparative analysis of the effectiveness of local therapy of chronic tonsillitis in children

Published:2018-12-29 Issue:6 Volume:63 Page:92-97
ISSN:2500-2228
Container-title:Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)
language:
Short-container-title:Ross. vestn. perinatol. pediatr.

Author:

Vladimirova T. Yu.¹^ORCID,Baryshevskaya L. A.¹^ORCID,Rodionova S. V.¹,Zeleva O. V.¹,Ayzenshtadt L. V.¹

Affiliation:

1. Samara State Medical University

Abstract

Objective: comparative analysis of the antibacterial efficacy of local treatment of chronic tonsillitis in children. Material and methods. The study included 116 children from 5 to 12 years old divided into two groups: Group 1 (main group) and Group 2 (control group), 59 and 57 patients respectively. All patients were subjected to examination of ENT organs, bacterial and viral antibodies check-up, and microbiological research of the tonsil’s lacunae. Group 1 was subjected to rinsing lacunas with a solution of furasol (potassium furazidin), Group 2 was subjected to rinsing lacunas with a solution of furatsilin (nitrofural). With similar input data, clinical examination and microbiological research in one month after the end of treatment showed higher efficacy of furazidine potassium in relation to the main pathogenic agents of the tonsil’s lacunae as compared to furatsilin. Conclusion: 1. The lacunae of the tonsils contain several microorganisms of different groups, which requires a more careful selection of the treatment in relation to bacteria with a high pathogenic potential. 2. Furasol is a highly effective antimicrobial drug for the local treatment of chronic tonsillitis, which helps to restore the biocenosis of the tonsils by affecting the pathogenic flora without adversely affecting saprophytic bacteria.Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported.

Publisher

The National Academy of Pediatric Science and Innovation

Subject

Pediatrics, Perinatology, and Child Health

Reference19 articles.

1. Dergachev V.S. K voprosu o klassifikatsii khronicheskogo tonzillita. Sbornik statei Vserossiiskoi konferentsii «Limfoepitelial'nye obrazovaniya verkhnikh dykhatel'nykh putei v norme i pri patologii». Belokurikha, 2002;76–88. [Dergachev V.S. Chronic tonsillitis classification. All-Russian Conference miscellany “Lymphoepithelial formations in upper airways on the normal and pathological level”. Belokurikha, 2002; 76–88. (in Russ)]

2. Dergachev V.S., Savenko V.I., Yakovlev V.V. Khronicheskii tonzillit – aktual'naya problema Altaiskogo kraya. Sbornik statei Vserossiiskoi konferentsii «Limfoepitelial'nye obrazovaniya verkhnikh dykhatel'nykh putei v norme i pri patologii». Belokurikha, 2002; 94–98. [Dergachev V.S., Savenko V.I., Yakovlev V.V. Chronic tonsillitis as an actual problem of Altai Kray. All-Russian Conference miscellany “Lymphoepithelial formations in upper airways on the normal and pathological level”. Belokurikha, 2002; 94–98. (in Russ)]

3. Myshentseva S.E., Baryshevskaya L.A., Tarasova N.V. Khronicheskii tonzillit kak prichina nevynashivaniya beremennosti. Ros otorinolaringol 2006; 2(21): 57–60. [Mishentsova S.E., Baryshevskaya L.A., Tarasova N.V. Chronic tonsillitis as a cause for pregnancy miscarriage. Ros otorinolaringol 2006; 2(21): 57–60. (in Russ)]

4. Kryukov A.I., Tovmasyan A.S., Zhukhovitskii V.G. Rol' mikroflory v etiologii khronicheskogo tonzillita. Vestn otorinolaringol 2010 3: 4–6. [Kryukov A.I., Tovmasyan A.S., Zhukhovitski V.G. Microflora in etiology of chronic tonsillitis. Vestn otorinolaringol 2010; 3: 4–6. (in Russ)]

5. Logunova E.V., Egorov V.I., Nasedkin A.N., Rusanova E.V. Ispol'zovanie fermentov s tsel'yu povysheniya effektivnosti antimikrobnoi fotodinamicheskoi terapii bol'nykh khronicheskim tonzillitom. Vestn otorinolaringol 2016; 81(2): 44–48. [Logunova E.V., Egorov V.I., Nasedkin A.N., Rusanova E.V. Enzymes for enhancement of antibacterial photodynamis therapy for chronic tonsillitis patients. Vestn otorinolaringol 2010; 81(2): 44–48. (in Russ)]