CONTRIBUTION OF PROFESSOR N.F. FILATOV (1847–1902)

Abstract

It was noted that during 25 years of scientific and teaching activity N. F. Filatov has made a significant contribution to the development of world Pediatrics. He is the author of over 70 scientific works, including «A short textbook of pediatric diseases» (1893), that was published in 12 editions, and «Clinical lectures» (1900). His monograph «Lectures on acute infectious diseases» (1885) was published in 4 editions, «Semiotics and diagnosis of childhood diseases» (1890) – 9 editions, it istranslated into German, Czech, Italian, Hungarian and French. Many generations of pediatricians have studied on N.F. Filatov’s monographs and manuals. He described the infectious disease named Filatov scarlatinal rubella. Later it was described by the British physician Dukes; one of the presently used names of the disease is Filatov-Dukes disease. In the first edition of «Lectures on infectious diseases» N. F. Filatov described not known until that time infectious mononucleosis, which he called idiopathic inflammation of the cervical lymphatic nodes. The disease is now often called the Filatov’s disease. In 1895 N. F. Filatov, described an important diagnostic sign of measles – the appearance in the catarrhal period of illness of grayish-white lesions on the mucose membrane of lips and cheeks 1–2 days prior to the appearance of rash. As was established later, this sign was first described by A. P. Belsky in 1890, then, independently, by N.F. Filatov, and in 1896 by Koplik. In the literature, this symptom is known as Belsky-Filatov-Koplik spots. N.F. Filatov described the pathogenesis of some forms of oedema syndrome in children, published works on prolonged afebrile forms of the flu. N.F. Filatov was developing a clinical-physiological direction in Pediatrics. He created a large school of native pediatricians. Among his students were famous pediatricians V.I. Molchanov and G.N. Speransky.