The clinical relevance of the microelements content in newborns after perinatal asphyxia

Author:

Gasanov S. Sh.1,Sadigova Sh. A.1,Babaeva B. A.1

Affiliation:

1. Azerbaijan Medical University

Abstract

Research purpose. To identify the correlation between the clinical signs of neonatal adaptation in the dynamics and the content of trace elements in the serum of newborns of different gestational ages who underwent perinatal asphyxia (main group): 41 premature infants and 27 full-term children.Results. It was found that there was a direct significant correlation between the concentration of trace elements (Mg, Fe, Zn, Cu), gestational age and Apgar grades (5th minute) in n prematurely born babies during the period of acute adaptation (3-5 days). Reliable feedback was established between the clinical signs of posthypoxic damage to the central nervous system, suppression syndrome and the content of Fe, Mg and Zn, as well as a weakening of muscle tone and the content of Zn and Mg. In full-term babies, the correlation between the content of Fe, Zn, Mg in the blood serum and clinical indicators was expressed more clearly. In these children, a significant positive correlation was observed between the Ca content in the blood and the syndrome of neuro-reflex excitability.Conclusion. The determination of trace elements in blood serum in newborns in the dynamics of the neonatal period (3-5th and 21-28th days of life) makes it possible to predict the course and severity of hypoxic-ischemic damage to the Central nervous system.

Publisher

The National Academy of Pediatric Science and Innovation

Subject

Pediatrics, Perinatology and Child Health

Reference9 articles.

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4. Bryksina E.Yu., Bryksin V.S., Bushtyreva I.O. Pathogenetic aspects of perinatal lesions of the Central nervous system and features of the neurological status of premature infants. Sovremennye problemy nauki obrazovaniya 2015; 4: 410 (in Russ.)

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