Affiliation:
1. Kazan State Medical University; Children’s Republican Clinical Hospital
2. Children’s Republican Clinical Hospital
Abstract
Lymphangioma is a benign neoplasm caused by a congenital malformation of the lymphatic vessels.Purpose. To study the possibility of momentary radical removal of lymphangioma in children based on a prospective cohort study in parallel groups.Characteristics of children and research methods. The article presents the results of treatment of 152 patients with lymphangioma, reported from the Department of Vascular Surgery of the Children’s Republican Clinical Hospital of Tatarstan. All patients were divided into 3 groups according to the applied method of treatment. The patients in Group 1 (n=95) underwent radical removal of lymphangioma, patients in Group 2 and Group 3 underwent partial removal followed by sclerotherapy of the residual cavity of the lymphangioma.Results. The authors observed relapse in 17 (11.2%) cases, 11 of these cases were observed after previous operation of complete excision (Group 1). According to the study of the distribution of relapses, there was no difference between the groups.Conclusion. Momentary radical excision of lymphangioma is implementable in 63.3% of cases. If it is impossible to remove lymphangioma completely they use partial excision and sclerotherapy of the residual cavity. The probability of relapse does not increase in case of impossibility to remove lymphangioma completely. Minimal invasive procedure is a priority of modern surgery, as it reduces surgical trauma, facilitates postoperative period and improves cosmetic result.
Publisher
The National Academy of Pediatric Science and Innovation
Subject
Pediatrics, Perinatology and Child Health
Reference14 articles.
1. Перельман М.И., Юсупов И.А., Седова Т.Н. Хирургия грудного протока. Москва: Медицина, 1984; 75—85. [Perel'man M.I., Yusupov LA., Sedova T.N. Thoracic duct surgery. Moscow: Meditsina, 1984; 75—85 (in Russ.)]
2. Smith D. W., Jones K.L. Recognizable patterns of human malformations: genetic, embryologic and clinical aspects. 3d ed. Philadelphia: Saunders, 1982; 472.
3. Byrne J., Blanc W.A., Warburton D., Wigger J. The significance of cystic hygromas in fetuses. Hum Pathol 1984; 15: 61. DOI: 10.1016/S0046-8177(84)80331-7
4. Huang H.Y., Ho C.C., Huang P.H, Hsu S.M. Co-expression of VEGF-C and its receptors, VEGFR-2 and VEGFR-3, in endothelial cells of lymphangioma. Implication in autocrine or paracrine regulation of lymphangioma. Lab Invest 2001; 81: 1729–1734.
5. Puri P. Newborn Surgery. Second Edition. London: ARNOLD 2009; 31.