Affiliation:
1. Novosibirsk State Medical University
2. Children’s City Clinical Hospital No. 6
Abstract
The article discusses the main risk factors for the formation of insufficiency and deficiency of vitamin D in children. Particular attention is paid to the course and dietary preferences of the mother during pregnancy, the intake of vitamin and mineral complexes, the nutrition of the child after birth, the type of feeding, the subsidy of vitamin D preparations and complementary foods. 1246 children under four years of age with no history of vitamin D deficiency were examined. With clinical manifestations of rickets, 52 children were identified, who underwent determination of 25(OH) D in serum, while low availability was detected in 21.1%, vitamin D insufficiency — in 63.4% of children, deficiency — in 15.3% of cases. There was an interaction between the use of dairy products enriched with a vitamin-mineral complex containing vitamin D and Ca, the use of therapeutic doses of vitamin D, and an increase in the level of 25 (OH) D in the blood serum.
Publisher
The National Academy of Pediatric Science and Innovation
Subject
Pediatrics, Perinatology and Child Health
Reference20 articles.
1. Romanenkova E.M., Zubkova N.A. Vitamin D-deficient rickets in a teenager: a clinical case. Russian Bulletin of Perinatology and Pediatrics. Rossiyskiy Vestnik perinatologii i pediatrii 2020; 65(4): 356–357. (in Russ.)
2. Rasulova N.A., Rasulov A.S., Sharipov R.X., AxmedovaM.M., Irbutaeva L.T. Assessment of the significance of the level of 25 (OH) D3 in blood serum and its effect on the prevention of rickets in children of the 1st year of life. Dostizheniya nauki i obrazovaniya 2019; 11(52): 45–49. (in Russ.)
3. Namazova-Baranova L.S., Zaharova I.N., Gromova O.A., Mal’cev S.V., Borovik T.Je., Pludovski P. et al. Vitamin D deficiency in children and teenagers of the Russian Federation: modern approaches to correction. Moscow: Pediatr, 2018; 96. (in Russ.)
4. Burt L.A., Gaudet S., Kan M., Rose S.M., Billington E.O., Boyd S.K. et al. Methods and procedures for: a randomized double-blind study investigating dose-dependent longitudinal effects of vitamin D supplementation on bone health. Contemporary Clinical Trials 2018; 67: 68–73. DOI: 10.1016/j.cct.2018.02.009
5. Stoffers A.J., Weber D.R., Levine M.A. An Update on Vitamin D Deficiency in the twenty-first century: nature and nurture. Curr Opin Endocrinol Diab Obes 2022; 29(1): 36–43. DOI: 10.1097/MED.0000000000000691