Systemic Lupus Erythematosus with neuropsychiatric manifestations in a child: case report and review of the international recommendations for the diagnostics and management

Abstract

The article describes a clinical case of a teenage girl with systemic lupus erythematosus with neuropsychiatric manifestations. The overview part describes modern approaches to the diagnosis and treatment of children with systemic lupus erythematosus with central nervous system lesions. The authors describe actual Russian and international clinical recommendations, they pay particular attention to the imperfection and inconsistency of classifications, differences in terminological systems, and the features of the rheumatologists’ and psychiatrists’ clinical practice. They provide the recommendations on the correct diagnosis wording in children with neuropsychiatric symptoms as a part of autoimmune disease. The article substantiates the necessity of an interdisciplinary approach and the cooperation of pediatric rheumatologists, psychiatrists, neurologists, clinical psychologists.