Immune system in development and progression of viral myocardial damage-Reference-Cited by-同舟云学术

Immune system in development and progression of viral myocardial damage

Published:2021-07-01 Issue:3 Volume:66 Page:27-33
ISSN:2500-2228
Container-title:Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)
language:
Short-container-title:Ross. vestn. perinatol. pediatr.

Author:

Khegai I. M.¹^ORCID,Trunina I. I.²^ORCID,Chebotareva T. A.³^ORCID,Khodikyan G. K.⁴^ORCID,Shumilov P. V.¹^ORCID

Affiliation:

1. Pirogov Russian National Research Medical University

2. Pirogov Russian National Research Medical University; Bashlyaeva Children’s Municipal Clinical Hospital

3. Russian Medical Academy of Continuing Professional Education

4. Russian Presidential Academy of National Economy and Public Administration

Abstract

This review demonstrates the role of the immune system in the development and progression of cardiac pathology caused by viral infection. The authors describe the role of lymphocytes (T- helper-17–Th17) in the viral persistence in myocardial tissue. They provide the information on increased level of interleukin-17A, the main Th17 cytokine in patients with dilated cardiomyopathy, which proves role of these cells in the progression of cardiac pathology. They discuss the role of T regulatory (Treg) lymphocytes in inflammatory heart disease.

Publisher

The National Academy of Pediatric Science and Innovation

Subject

Pediatrics, Perinatology and Child Health

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