Odontogenic Myxoma: Presentation of a Case and Literature Review

Abstract

According to the World Health Organization, maxillo-mandibular odontogenic myxoma is a benign tumor of mesenchymal origin. Its frequency, rare etiology, pathogenesis and therapeutic modalities are often discussed in the literature. It is a rare tumor that accounts for 0.41% to 7.19% of maxillo-mandibular tumors. In this present study, we reported a case of odontogenic myxoma of the left jaw that had progressed for several years, in a 25-year-old patient referred to the odontostomatology department of the Idrissa Pouye General Hospital by his attending dentist. The onset of symptoms went back three years. The volume of the mass evolved gradually and slowly over time. The medical examination did not reveal any particular medico-surgical history, or associated general signs. The intraoral examination revealed on inspection a tumor mass occupying the vestibular premolo-molar region of the left maxilla and measuring approximately five centimeters along its longest axis. This mass was bumpy in shape and reddish in color in places. On palpation, the mass was painless, mobile, of firm consistency, not bleeding on contact. Maxillofacial computed tomography revealed the presence of a spontaneously isodense, budding osteolytic process with lobulated contours, blowing the left maxilla in its anterior part. It extended into the hallway and made contact with the inside of the cheek, but did not invade it. The therapy was surgical under general anesthesia. No recurrence was observed at 9 months later. Maxillo-mandibular odontogenic myxoma is a rare, benign and locally invasive tumor. Its odontogenic origin remains the most likely. The clinical aspects or the radiographic presentation are not characteristic and make the differential interpretation difficult. A biopsy is mandatory for the establishment of a final diagnosis. The treatment is surgical. Rigorous monitoring is required during the first two postoperative years, as recurrences are not uncommon.