Sesquiterpene lactones. XXXII. Guaianolides in species from the genus Chartolepis Cass.

Abstract

Differences in the composition of the "lactone fraction" of 4 species from the genus <em>Chartolepis</em> Cass. were observed. Cynaropierin was isolated from the above-ground parts of <em>Chartolepis intermedia</em> Boiss. and the occurrence there of grossheimin was confirmed. The following compounds were isolated from the above-ground parts of <em>Chartolepis glastifolia</em> (L.) Cass.: centaurepensin, repin, cebellin C, acroptillin, cebellin D, cynaropicrin, cebellin F and janerin. Centaurepensin, repin, cebellin C, acroptillin, cynaropicrin, janerin and a new guaianolide, pterocaulin were isolated from the herb <em>Chartolepis biebersteinii</em> Jaub. et Spach. In addition to the lactones found in <em>Chartolepis biebersteinii, Chartolepis pterocaula</em> (Trautv.) Czer. also accumulated grossheimin.