Clinical Profile and in Hospital Outcome of Cerebral Venous Sinus Thrombosis at Tertiary Care Centre of Central India

Abstract

Objectives: The objectives of the study are as follows: Clinical profile and in hospital outcome of cerebral venous sinus thrombosis (CVST) at tertiary care centre in central India. To study clinical presentation and outcomes of CVST. Material and Methods: A cross-sectional study was performed in a tertiary care centre from October 2020–October 2022. All patients suspected to have CVST based on clinical history and examination were evaluated but only those with confirmed diagnosis (based on neuroimaging) of CVST were taken for study. Results: Total of 62 patients were studied, most common age group was between 21 and 30 years. Among them males and females are 61.29 and 38.71, respectively. In our study, we found dehydration (62.90%) as the most common predisposing risk factor of CVST, followed by alcohol (48.38%). Headache (83.87%) is the most common symptom and followed by vomiting (59.68%) and convulsion (48.39%), least common was altered sensorium. The most common sinuses involved were superior sagittal sinus (67.74%) and superior sagittal plus sigmoid sinus (14.52%). Among 62 patients, 48 are discharged (77.42%). Death was reported in 14 (22.58%) cases. Conclusion: CVST is an important cause of intracranial hypertension, seizures and stroke in young people. Clinical presentation is extremely variable and a high index of suspicion is needed. Magnetic resonance imaging brain with magnetic resonance venography is the current diagnostic modality of choice.