A case of acute hyperammonemic encephalopathy after initiation of 5-fluorouracil chemotherapy

Author:

Daly Timothy1,Prenatt Zarian1,Sagin Hannah1,Wen Sally1,Shah Kashyap2,Proothi Subhash3,Hehar Prabhdeep4

Affiliation:

1. Department of Internal Medicine, SLUHN, Bethlehem, Pennsylvania, United States,

2. Department of Cardiology, SLUHN, Bethlehem, Pennsylvania, United States,

3. Department of Hematology/Oncology, SLUHN, Bethlehem, Pennsylvania, United States,

4. Department of Anesthesia/Critical Care, SLUHN, Bethlehem, Pennsylvania, United States,

Abstract

5-fluorouracil is a chemotherapeutic agent that has been used for decades to treat a number of neoplasms. It has a number of adverse effects; however, we present a case of a seldom reported side effect in hyperammonemic encephalopathy that should be considered in patients presenting with altered mental status shortly after starting therapy.

Publisher

Scientific Scholar

Reference9 articles.

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