Abstract
The treatment of psoriatic arthritis (PsA) makes use of many agents. Most of them are used for the treatment of other forms of inflammatory arthritis or the management of cutaneous manifestations of psoriasis. Although a number of medications are effective in the treatment of both rheumatoid arthritis (RA) and PsA, trials involving some classes of biologic agents indicate that patients with RA and PsA may show different responses to certain drug classes. Treatment of the different elements of PsA includes coordinated interventions to address the major domains of the disease, including peripheral and axial arthritis, enthesitis, dactylitis, and skin and nail involvement.