Spontaneous regression of a thrombosed cerebral arteriovenous malformation in a patient with a prothrombotic state associated with multiple myeloma: A case report and literature review

Author:

Arenas-Ruiz José A.1,Hernández-Álvarez Nickjail2,de Llano Juan P. Navarro-Garcia2,Ponce-Ayala Aurelio2,Nathal Edgar2

Affiliation:

1. Department of Neurosurgery, Hospital Universitario “Dr. José Eleuterio González” UANL, Monterrey, Nuevo León,

2. Department of Neurosurgery, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México, Mexico.

Abstract

Background: Cerebral arteriovenous malformations (AVMs) are pathologic communications between veins and arteries of the brain vasculature. Its spontaneous regression is rare, and many factors have been described in the effort to explain this phenomenon, including a hypercoagulable state. Case Description: We present the case of a spontaneous unruptured AVM regression in a patient where thrombosis of the malformation was found, probably due to a prothrombotic state associated with multiple myeloma (MM). Conclusion: We aim to contribute to the study of this rare phenomenon, presenting the relationship between a hypercoagulable state caused by MM and the spontaneous AVM regression that has not been previously reported.

Publisher

Scientific Scholar

Subject

Neurology (clinical),Surgery

Reference19 articles.

1. Spontaneous angiographic obliteration of cerebral arteriovenous malformations;Abdulrauf;Neurosurgery,1999

2. Spontaneous thrombosis of the main draining vein revealing an unruptured brain arteriovenous malformation;Cao;Interv Neuroradiol,2015

3. Thrombosis in multiple myeloma (MM);Cesarman-Maus;Hematology,2012

4. Cerebral venous thrombosis in an individual with multiple myeloma treated with lenalidomide;Eudo;J Am Geriatr Soc,2011

5. Spontaneous disappearance of a cerebral arteriovenous malformation: Case report;Hamada;Neurosurgery,1994

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