Severe acute respiratory syndrome coronavirus 2: Mutations and variants of concern – the Indian scenario-Reference-Cited by-同舟云学术

Severe acute respiratory syndrome coronavirus 2: Mutations and variants of concern – the Indian scenario

Published:2021-05-29 Issue: Volume:6 Page:66-71
ISSN:2456-3994
Container-title:International Journal of Molecular & Immuno Oncology
language:en
Short-container-title:IJMIO

Author:

Darling H. S.¹,Parikh Purvish²,Vaishnav Radhika³,Verma Amit⁴,Gulia Ashish⁵,Kapoor Akhil⁶,Singh Randeep⁷

Affiliation:

1. Department of Medical Oncology and Hemato-Oncology, Command Hospital Air Force, Bengaluru, Karnataka, India

2. Department of Precision Oncology and Research, Shalby Hospital, Mumbai, Maharashtra, India

3. Department of Anatomy and Physiology, College of Arts Science and Education, IvyTech Community College, USA,

4. Department of Molecular Oncology and Cancer Genetics, Max Hospital, New Delhi, India

5. Bone and Soft Tissue, Tata Memorial Hospital, Mumbai, Maharashtra, India

6. Department of Medical Oncology, TMH Varanasi, Varanasi, Uttar Pradesh, India

7. Department of Medical Oncology, Narayana Superspeciality Hospital, Gurugram, Dharamshila, India

Abstract

When India did well to contain the first wave of coronavirus disease 2019 (COVID-19) pandemic, none of us had an inkling of the magnitude that the second wave was going to take. One of the main reasons for the resurgence is several new mutants of this virus – the important ones for our country being UK Variant, Indian Double mutant, South African, and Brazil variants. Questions regarding their impact on virulence, pathogenicity, transmissibility, detection, clinical symptomatology, morbidity, mortality, potential curability, and possibly decreased therapeutic/ vaccine efficacy are being ascertained. We hereby summarize the importance of these variants with respect to Indian scenario, with emphasis on implications regarding COVID-19 diagnosis and efficacy of current vaccines.

Publisher

Scientific Scholar

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