Lytic lesions in bone in a CKD patient, brown tumor is a must on the differential

Author:

Rodrigues Norris Moses1,Ohri Alpana1,Udani Amish2,Shah Chintan2,Agrawal Srishti1

Affiliation:

1. Department of Pediatrics, Bai Jerbai Wadia Hospital for Children, Mumbai, Maharashtra, India,

2. Division of Pediatric Nephrology, Bai Jerbai Wadia Hospital for Children, Mumbai, Maharashtra, India,

Abstract

Brown tumor is a focal lesion of giant cells without neoplastic potential encountered in association with hyperparathyroidism. These lesions can occur anywhere in the skeletal system producing various local symptoms. In this case report, we present a 15-year-old boy with stage 5 chronic kidney disease (CKD) on maintenance hemodialysis who presented with hip pain for 1 week. On investigating, the patient had normal parathyroid levels (PTH) but the previous metabolic bone disorder (MBD) parameters revealed a high PTH. Imaging showed expansile radiolucent lesions involving the left hip. Considering the clinical, metabolic and the radiological picture the patient was diagnosed to have brown tumor with secondary hyperparathyroidism and was treated with Cinancalcet, vitamin D and immobilization with a brace.

Publisher

Scientific Scholar

Reference8 articles.

1. Brown tumors: A case report and review of the literature;Can;Case Rep Nephrol Dial,2016

2. Brown tumor as a result of secondary hyperparathyroidism in chronic renal disease;de Santana Mascarenhas;J Oral Diagn,2016

3. Chronic kidney disease presenting with brown tumors in the mandible;Singh;Cureus,2022

4. Unusual presentation of primary hyperparathyroidism: Report of three cases;Huang;BMC Med Imaging,2015

5. A rare complication of secondary hyperparathyroidism. Brown tumor of the maxilla and mandible;Pinar Sumer;Saudi Med J,2004

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