Large parotid and cheek infantile hemangiomas refractory to medical treatment: Is there a role for embolization?

Abstract

Objectives: The aim of this study was to evaluate the results of transarterial embolization (TAE) as a stand-alone treatment for large parotid and cheek infantile hemangiomas (IHs) that are refractory to medical treatment. Material and Methods: We retrospectively reviewed patients with head and neck IHs who underwent TAE at two single tertiary centers. We then analyzed the clinical and angiographic data of those patients with IHs located in the parotid and/or cheek regions. Results: A total of 38 patients with head and neck IHs were treated with TAE. Sixteen patients had a follow-up 2 months or more after treatment; from these patients, 6 IHs were located in the parotid or cheek regions. Four of the six tumors were in the proliferative phase. After TAE, almost 100% of angiographic obliteration of the IHs was attained. There was a complete shrinking of the tumor mass in all patients within a period of 2–5 months. One partially reversible complication occurred. Conclusion: Our preliminary results showed that TAE may be a useful therapeutic treatment not only before surgery but also as upfront and definitive therapy for parotid and cheek IHs.