Wolf in sheep’s clothing

Abstract

Autoimmune encephalitis (AE) is an immune-mediated disease with a varied clinical spectrum. Osmotic demyelination is a condition characterized by hypernatremia following an episode of correction for hyponatremia. Our case report is about a patient who presented with features of central diabetes insipidus and an imaging diagnosis of osmotic demyelination. Magnetic resonance imaging of the brain, which later turned out to be AE based on the positive auto-antibodies.