Primary pulmonary osteosarcoma: A rare malignancy of the lung with histopathologic correlation

Abstract

Primary pulmonary osteosarcoma (PPO) is an uncommon aggressive mesenchymal neoplasm of the lung characterized by the production of osteoid matrix. Calcified metastases from osteosarcoma of bone are more common in the lung rather than PPOs, and the differentiation between these two entities is important for the management. The diagnosis of PPO requires exclusion of primary osteosarcoma elsewhere in the body and also histopathological confirmation. We report a case of primary osteosarcoma of the lung with a brief review of literature.