Sebaceous gland carcinoma of ocular region in India: A brief literature review for disease management

Abstract

Sebaceous gland carcinoma (SGC) is slow growing, but the most aggressive and lethal eyelid malignancy. Histologically, SGC can be classified based on cell types, cytoarchitecture, and growth patterns. A previously published article illustrates the molecular genetic framework stating the drivers of sebaceous carcinoma. Today, every effort has been made to treat and eradicate ocular disease, therefore, early diagnosis and appropriate management are required to use a multimodal approach that can reduce the mortality rate in patients with SGC. Treatment with the conventional technique has improved visual and systemic prognosis, however, therapeutic target to treat cancer is a much better option than other modalities. Thus, new insight into the natural and molecular-oriented treatment modalities may lead to the development of new effective strategies, along with the conventional method.