Phalangeal microgeodic syndrome, COVID-19, and antinuclear antibodies in a child: A case report

Abstract

Phalangeal microgeodic syndrome (PMS) is a rare rheumatological disease affecting children strongly associated with cold weather. It is considered to be benign and self-limiting, with most cases resolving in warmer months, and no studies have investigated its association to autoantibodies or viral infection. In this peculiar case, a 12-year-old child with the previous COVID-19 infection developed PMS that did not improve in the warm weather and, subsequently, Raynaud’s phenomenon and facial rash. With the increasing number of new studies showing the correlation between COVID-19 and autoimmunity, this case report highlights a plausible link between COVID-19, PMS, and autoimmunity in the pediatric population that should be investigated further.