Female monozygotic twins with sacral myelomeningocele

Author:

Adebayo Bamidele Oludele1,Tiamiyu Liadi Olanrewaju1,Adetunmbi Babatunde1,Adegboyega Rilwan Omogbolahan1,Etagar Charles Oghenerukevwe1,Kanu Okezie Obasi2,Bankole Olufemi2

Affiliation:

1. Department of Surgery, Federal Medical Center, Abeokuta, Ogun, Nigeria

2. Department of Surgery, College of Medicine, University of Lagos/Lagos University Teaching Hospital, Lagos, Nigeria.

Abstract

Background: Concurrent myelomeningocele in twins is a rare clinical presentation, only reported twice in Nigeria. Case Description: We present a set of identical female twins from Nigeria. Both twins were females that presented at 3 years with low back swelling since birth, associated with bisphincteric dysfunction but normal motor and sensory functions in the lower extremities. They had repair of myelomeningocele 2 months after presentation and there was no new deficit postoperatively. There was no family history of neural tube defects and it would have been good to do genetic studies in this case but we do not have facilities for such. Conclusion: This is the first reported case of identical twins with concurrent myelomeningocele and preserved motor functions in the lower limbs in Nigeria and West Africa.

Publisher

Scientific Scholar

Subject

Neurology (clinical),Surgery

Reference17 articles.

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4. Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects;Deak;Birth Defects Res A Clin Mol Teratol,2008

5. Effects and safety of periconceptional oral folate supplementation for preventing birth defects;De-Regil;Cochrane Database Syst Rev,2015

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