Spontaneous epidural hematoma induced by rivaroxaban: A case report and review of the literature

Author:

Siahaan Andre Marolop Pangihutan1,Tandean Steven1,Nainggolan Bahagia Willibrordus Maria2

Affiliation:

1. Department of Neurosurgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

2. Department of Undergraduate Program in Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Abstract

Background: Trauma is the most frequent reason for epidural bleeding. However, numerous investigation had discovered that anticoagulants such as rivaroxaban could cause epidural hematoma. Here, we present a case of epidural hematoma in young man who got rivaroxaban as treatment of deep vein thrombosis. Case Description: A 27-year-old male with a history of deep vein thrombosis and one month of rivaroxaban medication presented with seizure and loss of consciousness following a severe headache. A CT scan of the head revealed epidural bleeding, and emergency blood clot removal was performed. As a reversal, prothrombin complex was utilized. Conclusion: Rivaroxaban has the potential to cause an epidural hemorrhage. Reversal anticoagulant should be administered before doing emergency surgery.

Publisher

Scientific Scholar

Subject

Neurology (clinical),Surgery

Reference38 articles.

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2. Oral rivaroxaban for symptomatic venous thromboembolism;Bauersachs;N Engl J Med,2010

3. Resuming anticoagulant therapy after intracerebral bleeding;Becattini;Vascul Pharmacol,2016

4. New Oral anticoagulants and the risk of intracranial hemorrhage: Traditional and bayesian meta-analysis and mixed treatment comparison of randomized trials of new oral anticoagulants in atrial fibrillation;Chatterjee;JAMA Neurol,2013

5. Progressive epidural hematoma in patients with head trauma: Incidence, outcome, and risk factors;Chen;Emerg Med Int,2012

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