Stereotactic placement of dual lumen catheter system for continuous drainage, irrigation, and intraventricular antibiotic therapy for treatment of brain abscess with ventriculitis – A case report and literature review

Author:

Policicchio Domenico1,Cosco Lucio2,Mauro Giuseppe1,Iannello Alfonso Nicola1,Santaguida Luigi3,Vescio Virginia4,Dipellegrini Giosué5

Affiliation:

1. Department of Neurosurgery, Azienda Ospedaliero Universitaria Renato Dulbecco di Catanzaro, Catanzaro, Italy

2. Unit of Infectious and Tropical Diseases, Azienda Ospedaliero Universitaria “Renato Dulbecco” di Catanzaro, Catanzaro, Italy

3. Unit of Biomedical Engineering, Azienda Ospedaliero Universitaria “Renato Dulbecco” di Catanzaro, Catanzaro, Italy

4. Department of Radiology, Azienda Ospedaliero Universitaria “Renato Dulbecco” di Catanzaro, Catanzaro, Italy

5. Department of Neurosurgery, Azienda Ospedaliero Universitaria di Sassari, Sassari, Italy.

Abstract

Background: Cerebral abscesses complicated by ventriculitis present significant treatment challenges, often associated with high morbidity and mortality. Traditional management approaches, including systemic antibiotic therapy and external ventricular drainage (EVD), face limitations due to the blood-brain barrier and risks of catheter-related complications. This report discusses a case where the dual-lumen catheter system, an innovative neurosurgical tool integrating continuous irrigation with drainage, was employed. Case Description: A patient presented with a cerebral abscess ruptured into the ventricle, leading to ventriculitis. Conventional treatment options were limited due to the abscess’s deep and eloquent location and the associated risk of complications from standard EVD. The dual lumen system was chosen for its ability to provide continuous irrigation and drainage, effectively addressing issues of catheter blockage and enhancing localized antibiotic delivery. The system was used to create a single stereotactic tract for simultaneous treatment of the abscess and ventriculitis. This approach allowed for a more controlled and effective treatment process, resulting in rapid resolution of the conditions without chronic hydrocephalus development or further complications. Conclusion: The use of the dual lumen system represented a significant advancement in this case, addressing the limitations of conventional treatments. Its ability to maintain intracranial pressure within optimal limits while providing localized, continuous treatment was pivotal. This case highlights the potential of the dual lumen catheter in managing complex neurosurgical infections and underscores the need for further research to establish its efficacy in broader clinical applications.

Publisher

Scientific Scholar

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