Individualised homoeopathy in the treatment of hyperuricaemia: A single-arm clinical trial

Abstract

Objectives: Hyperuricaemia is a metabolic disorder characterised by abnormally high levels of uric acid in the blood, which can lead to gout, kidney stones, and cardiovascular disease. While some studies have suggested that homoeopathic remedies may be effective in reducing uric acid levels and improving symptoms in patients with hyperuricaemia, there is limited scientific evidence to support their use as a primary treatment. Material and Methods: An open-label, prospective, non-controlled, and pre-post comparison clinical trial was conducted on 30 patients diagnosed with hyperuricaemia to assess the effect of individualised homoeopathic medicines after 3 months of treatment. Eligible patients were aged between 20 and 65 years, of both sexes and had a serum uric acid level >6 mg/dL in women and >7 mg/dL in men. Patients taking urate-lowering agents were excluded from the study. Serum uric acid level was used as the primary outcome measure. Results: The study found that homoeopathic treatment was associated with a significant reduction in serum uric acid levels (mean difference ± standard error: −2.04 ± 0.16, P < 0.001) after 3 months of treatment. There were no reported adverse effects associated with the treatment. Conclusion: This clinical trial provides preliminary evidence to support the potential effect of homoeopathic treatment for hyperuricaemia. However, further research with larger sample sizes and more rigorous study designs is needed to confirm these findings and determine the optimal use of homoeopathy in the management of hyperuricaemia.