Application of HPLC in Biomedical Research for Pesticide and Drug Analysis

Author:

Saha Sourav1,Mallik Sandip2,Debnath Bikash3,Singh Waikhom Somraj4,Ikbal Abu Md Ashif5,Manna Kuntal6

Affiliation:

1. Department of Pharmaceutical Chemistry, Regional Institute of Pharmaceutical Science and Technology, Agartala, Tripura, India

2. Department of Pharmaceutics, Guru Nanak Institute of Pharmaceutical Science and Technology, Kolkata, West Bengal, India

3. Department of Pharmaceutics, Regional Institute of Pharmaceutical Science and Technology, Agartala, Tripura, India

4. Department of Allied Health Sciences, The ICFAI University, Agartala, Tripura, India

5. Department of Pharmaceutical Sciences, Assam University (A Central University), Silchar, Assam, India

6. Department of Pharmacy, Tripura University (A Central University), Agartala, Tripura, India,

Abstract

Compared to traditional liquid chromatography, high-performance liquid chromatography (HPLC) delivers better results for analyzing unknown compounds. It permits faster resolution time, better peak shapes, repeatable responses, and greater precision. A comprehensive literature search has been conducted using online academic databases such as Google Scholar, PubMed, Web of Science, and Scopus, using keywords such as HPLC, pesticide analysis, drugs analysis, chromatographic conditions, and HPLC Column type. Total 75 number of articles were collected from peer-reviewed journals. With the help of literature review we have summarized the chromatographic condition of 30 drug candidates and 27 pesticide candidates. The study’s findings can guide future researchers to understand the chromatographic parameters of drugs and pesticides.

Publisher

Scientific Scholar

Subject

General Medicine

Reference75 articles.

1. Hydrophilic interaction liquid chromatography (HILIC)-a powerful separation technique;Buszewski;Anal Bioanal Chem,2012

2. A theory of chromatography;Wilson;J Am Chem Soc,1940

3. A review of chromatograph: Principal, classification, application;Dongare;Int J Humanit Soc Sci,2023

4. The theory of chromatography;DeVault;J Am Chem Soc,1943

5. Separation techniques: Chromatography;Coskun;North Clin Istanb,2016

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