Association between socio-demographic factors and blood groups with risk of diabetes mellitus in Dangila hospital, Awi Zone, North West Ethiopia

Abstract

Introduction: Diabetes mellitus (DM) is a metabolic disease which is categorized as hyperglycemia. This disease is a multi-factorial trait that appears by interactions of genetic, immunological, and environmental factors. Materials and Methods: The study was conducted through case–control method of study in Dangila, Ethiopia. The total number of individuals included as study subjects was 403, of these 201 were diabetic patients (81 type I and 120 type II diabetic patients) and 202 were non-diabetics patients. From 403 participants, 225 were males and 178 were females. The data were analyzed using SPSS version 21.0. Results: A significant association was obtained between sex, age, marital status, blood group and Rh factors with diabetes mellitus but not with residence and family histories. Male from sex, above 40 years from age, married from marital status were more susceptible for diabetes, contrary females, 16-40 years and singles were lower risk of diabetic than other comparable categories. In case of blood group, type A was more susceptible and blood type O and AB were lower risk rate of diabetes mellitus. Additionally blood AB/Rh negative individuals were not affected by type I diabetes mellitus. Conclusion: The socio-demographic factor sex, age, and marital status showed a significant association but family history and residence did not show a significant association with DM. In blood groups, the other important point that observed was, no one founds who had AB blood groups that diagnose type one DM. The majority of the study participants had Rh-positive, though the significant difference between diabetic and non-diabetic was observed only in Rh negatives.