Different facets of intracranial central nervous system lymphoma and its imaging mimics

Author:

Kwok Hoi Ming1,Li Kwok Yan1,Chan Rois L. S.1,Chan Chi Hin2,Wong Stephen Ka Hon1,Lee Chiu Man1,Cheng Lik Fai1,Ma Johnny Ka Fai1

Affiliation:

1. Department of Diagnostic and Interventional Radiology, Princess Margaret Hospital, Kowloon, Hong Kong, China,

2. Department of Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital, Kowloon, Hong Kong, China,

Abstract

Lymphomas of the central nervous system (CNS) are broadly classified into primary CNS lymphoma (PCNSL) and secondary CNS lymphoma (SCNSL). PCNSL refers to lymphoma restricted to the brain, leptomeninges, spinal cord, or eyes without evidence of it outside the CNS at primary diagnosis, while SCNSL refers to secondary CNS involvement by systemic lymphoma. The brain is the most common site of involvement and intracranial CNS lymphoma has a highly variable imaging appearance and varies according to the patient’s clinical profile and immunity. This pictorial essay aims to illustrate the different facets of intracranial CNS lymphomas on neuroimaging. This enables radiologists to be familiarized with their key diagnostic features and differentiate from their differential diagnoses, leading to early diagnosis, and treatment.

Publisher

Scientific Scholar

Subject

Radiology, Nuclear Medicine and imaging

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