Granzyme B: A novel therapeutic target for treatment of atopic dermatitis-Reference-Cited by-同舟云学术

Granzyme B: A novel therapeutic target for treatment of atopic dermatitis

Published:2022-10-31 Issue: Volume:89 Page:166-169
ISSN:0973-3922
Container-title:Indian Journal of Dermatology, Venereology and Leprology
language:en
Short-container-title:IJDVL

Author:

Zhang Qian,Wang Qian,Zhang Li-Xia¹

Affiliation:

1. Department of Dermatology & Venerology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, China,

Abstract

Granzyme B is a serine protease that can play multiple roles in intracellular and extracellular perforin-dependent or non-perforin-dependent mechanisms. Granzyme B has been found to be an important factor involved in the pathogenesis of atopic dermatitis and is increased in both skin lesions and peripheral blood of atopic dermatitis patients. In this article, we review the correlation between granzyme B and atopic dermatitis to provide a novel therapeutic targeting option for clinical treatment of the latter.

Publisher

Scientific Scholar

Subject

Infectious Diseases,Dermatology

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