A Systematic Review based on the Use of Au- and Pt-based Nanoparticles along with H2 Blocker Medicines

Abstract

This study is a review and a cumulative piece of work on Pt- and Au-based nanoparticles and H2 blockers drugs. It has been studied that Pt- and Au-based nanoparticles are used more often in different biomedical applications. Nanoparticles based on these two metals are highly biocompatible and can be used for the diagnosis of various diseases through in vitro imaging, tissue engineering, and drug delivery. The compatibility of Pt- and Au-based nanoparticles is increased using polymer-nanocomposite hybrids, which can participate in delivering a large number of drugs to modulate and improve the biodistribution and uptake of drugs on the cellular level. Another part of this review focuses on H2 blocker drugs. These drugs are specific classes for the suppression of gastric juice or acids under different gastrointestinal conditions. Famotidine has also been reported as a marker drug for COVID-19 patients. This review provides cumulative information on H2 blocker drugs and nanoparticles in single articles and specifies their role in different treatments associated with different types of cancers, gastrointestinal disorders, and COVID-19.