99mTc-UBI 29-41 bone SPECT/CT scan in craniofacial Actinomyces israelii: Misdiagnosis of cranial bone tumor

99mTc-UBI 29-41 bone SPECT/CT scan in craniofacial Actinomyces israelii: Misdiagnosis of cranial bone tumor – A case report

Published:2020-12-16 Issue: Volume:11 Page:442
ISSN:2152-7806
Container-title:Surgical Neurology International
language:en
Short-container-title:

Author:

Cerda-Vargas María F. De la¹,Rangel José Antonio Candelas¹,Mata Elizabeth Meza²,Ramírez-Cárdenas Araceli³,Sandoval-Bonilla Bayron A.⁴

Affiliation:

1. Department of Neurosurgery, Hospital de Especialidades No. 71, Instituto Mexicano del Seguro Social, Torreón, Coahuila, México,

2. Department of Pathology, Hospital de Especialidades No. 71, Instituto Mexicano del Seguro Social, Torreón, Coahuila, México,

3. Graduate School of Neural and Behavioural Sciences, International Max Planck Research School, Tuebingen University, Tuebingen, Germany,

4. Department of Neurosurgery, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, México.

Abstract

Background: Actinomycosis is a rare infection, frequently misdiagnosed as a neoplasia. This chronic and granulomatous disease is caused by Actinomyces israelii species. Cervicofacial actinomycosis occurs in 60% of cases and the diagnosis is commonly made by histopathology study. Case Description: We report a case of fronto-orbital osteomyelitis initially misdiagnosed as a cranial bone meningioma, but later proved to be a case of actinomycosis. 99mTechnetium (99mTc) three-phase bone single-photon emission computed tomography/computed tomography (SPECT/CT) and 99mTc-ubiquicidin (UBI) 29-41 bone SPECT/CT scans were performed to corroborate the control of the infection. Conclusion: Craniofacial actinomycosis is the most common presentation of actinomycosis. However, it continues to be a rare and difficult disease to diagnose and is often confused with a neoplastic process. The 99mTc-UBI 29-41 bone SPECT/CT scan could be an auxiliary noninvasive diagnostic alternative and a follow-up method for these patients.

Publisher

Scientific Scholar

Subject

Clinical Neurology,Surgery

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